NFL Picks for 12/15/22
8:15 PM EST
Rotation # 301-302
49ers/Seahawks Over 43.5 (loss)
The 49ers will start Brock Purdy at QB again. Purdy is slightly banged up from his start last week but should be ready. The 49ers will be without Deebo Samuel tonight, but Brandon Aiyuk should step up, and the reliable George Kittle should have a big game. The Seahawks are a terrible defense and severely shorthanded this evening in their secondary. The 49ers will score at will, much like they did last week. Seattle should create scoring opportunities at home with running back Kenneth Walker back in the lineup. The Seahawks have plenty of suitable targets and should take advantage of a 49ers secondary that is also shorthanded. Seattle has a golden opportunity on their home field to get back in the NFC West race or, at the very least, get into a wildcard spot.