Picks for 9/22/25
NFL
8:15 PM EST
Rotation # 479-480
Lions/Ravens Over 53.5 (win)
The Ravens’ offense is a nightmare to stop, but it is even more challenging for a defense not at full strength. The Lions are thin on the defensive line, as Marcus Davenport will miss tonight’s game. They are already dealing with the loss of Josh Paschal, Alim McNeill, and Levi Onwuzurike. To slow down Lamar Jackson, you need to be at full strength, which is far from the case this evening. Baltimore has a big offensive line that opens up lanes for Derrick Henry and gives Jackson time to throw downfield or take off himself. The Lions have a well-balanced attack as Jared Goff has a lot of outstanding receivers, and Jahmyr Gibbs and David Montgomery are an exceptional 1-2 punch running the ball. Baltimore is also without the services of linebacker Kyle Van Noy. Both teams can score in bunches, and it never gets easier for a defense to stop the opponent when missing players who can make tackles and get after the quarterback. Take the Over.