NFL Picks for 11/21/22
NFL
8:15 PM EST
Rotation #475
49ers -9.5 over Cardinals (win)
49ers/Cardinals Over 43.5 (win)
Hola amigos! The game tonight between the Cardinals and the 49ers will be played in Mexico City, Mexico. Cardinals QB Kyler Murray will probably miss tonight’s game, but Colt McCoy is an adequate backup as he gets the ball out of his hands fast. The Cardinals will be without tight end Zach Ertz tonight but have plenty of great receivers like AJ Green, DeAndre Hopkins, and Rondale Moore. Look for James Connor to run the ball well and for McCoy to find his targets. The Cardinals impressed me last week with a backup quarterback and four offensive linemen out of the game due to injury against the Rams. Magic won’t strike twice tonight, but they will compete. Jimmy Garoppolo should have a field day tonight against a bad Arizona Defense. The 49ers have a ton of great running backs, and up and down the roster, they have many great receivers like Debbo Samuel, Brandon Aiyuk, and George Kittle at tight end. The 49ers should put up a lot of points against a bad defensive team, as head coach Kyle Shannahan is an offensive-minded coach. The 49ers might not be at home, but most of the fans are San Francisco fans. Look for the 49ers to blow out the Cardinals and look for the Cardinals to put up enough offense to help this go over the total. Take the 49ers and the Over. Both are straight bets. Buena Suerte! (Best of luck!)